SEREX Review
Identification of human tumor antigens by serological expression cloning – an online review on SEREX
Yao-Tseng Chen, M.D., Ph.D.
The original text of this review was published as:
Chen YT, Scanlan MJ, Obata Y, Old LJ. Identification of human tumor antigens by serological expression cloning. In: Rosenberg SA, editor. Principles and practice of the biologic therapy of cancer. 3rd ed. Philadelphia (PA): Lippincott Williams & Wilkins; 2000. pp. 557-70. ISBN 0-7817-2272-1
Permission has been granted to Cancer Immunity to reproduce the text and have it updated by one of the original authors in order to provide a “living” review online. This review should be cited as follows:
Chen YT. Identification of human tumor antigens by serological expression cloning: an online review on SEREX. Cancer Immun 2004 [updated 2004 Mar 10; cited 2004 Apr 1]. URL: http://www.cancerimmunity.org/serex
The text is divided into the following sections:
- Introduction
- Methodology
- SEREX: the technique and steps involved in the analysis of SEREX-defined antigens
- Modifications in the SEREX technique
- SEREX-defined antigens by tumor type
- Melanoma
- Esophageal Cancer
- Colon Cancer
- Gastric Cancer
- Renal Cancer
- Lung Cancer
- Breast Cancer
- Prostate Cancer
- Hepatic Cancer
- Ovarian Cancer
- Sarcoma
- Neuroblastoma
- Other Solid Tumors
- Hodgkin’s and Non-Hodgkin’s Lymphoma
- Leukemia
- Classification of SEREX-defined antigens
- Immunogenicity of SEREX-defined antigens
- Basis for the immunogenicity of SEREX-defined antigens
- Seroepidemiology of SEREX-defined antigens
- T cell recognition of SEREX-defined antigens
- Cancer Immunome
- References
Contact
Address correspondence to:
Yao-Tseng Chen, M.D., Ph.D.
Department of Pathology
Weill Medical College of Cornell University
New York, NY 10021
USA
ytchen@med.cornell.edu
Copyright © 2004 by Yao-Tseng Chen
